Gene therapy progress and prospects: magnetic nanoparticle-based gene delivery
نویسندگان
چکیده
منابع مشابه
Nanoparticle-mediated drug delivery and gene therapy.
Biomedical application of nanotechnology is a rapidly developing area that raises new prospect in the improvement of diagnosis and treatment of human diseases. The ability to incorporate drugs or genes into a functionalized nanoparticle demonstrates a new era in pharmacotherapy for delivering drugs or genes selectively to tissues or cells. It is envisioned that the transfer of nanoengineering c...
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Gene delivery holds promise to cure many inheritable or acquired diseases that are currently considered incurable. Liposomes are clinically well-established drug-delivery vehicles with promising properties, including biocompatibility, high drug-to-carrier ratios, and straightforward drug-encapsulation capability. However, widespread clinical use of this delivery system still requires better del...
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The first clinical gene delivery, which involved insertion of a marker gene into lymphocytes from cancer patients, was published 25 years ago. In this review, we describe progress since then in gene therapy. Patients with some inherited single-gene defects can now be treated with their own bone marrow stem cells that have been engineered with a viral vector carrying the missing gene. Patients w...
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ژورنال
عنوان ژورنال: Gene Therapy
سال: 2006
ISSN: 0969-7128,1476-5462
DOI: 10.1038/sj.gt.3302720